Category Archives: Uncategorized
New test for selection of RNA secondary structures
Bia developed a test for selection of non-coding RNAs. Her test uses the RNA secondary structure as proxy for its function. In contrast to previous work, she cannot only asses negative selection but also pinpoint structures with lineage specific changes … Continue reading
Two new lizard genomes
Rohit published his results on the comparison of two lizard genomes: Lacerta viridis and Lacerta bilineata. He sequenced both genomes with Illumina and PacBio, performed de-novo assemblies. The high quality assemblies allowed him to assess genome divergence, structural variations, and … Continue reading
wTO package for network analysis
Deisy turned our method for calculating weighted topological overlap (wTO) networks into an R package and published it in BMC Bioinformatics. The method was developed by Eivind Almaas for describing a transcription factor network in the prefrontal cortex of humans … Continue reading
Paper on human neurogenesis
Our group contributed to a research project of Volker Busskamp’s lab on the role of miR-124 during human neurogenesis. Deisy uncovered a transcription factor network that is involved in the differentiation of neurons from induced pluripotent stem cells and determined … Continue reading
Network evolution paper
Stefano’s paper on the evolution of the transcription factor network in the primate prefrontal cortex has been published in GBE. While the functional output of that network seems to be conserved across the investigated primates, the network has evolved more … Continue reading
EVOP moved to the FU
After six successful editions of our Programming for Evolutionary Biology course in Leipzig, we are currently running the first edition at the FU. The outline and philosophy of the course stayed the same; just the location changed. We, organizers, lecturers, … Continue reading
New Postdoc: Vladimir Jovanovic
We are welcoming the second postdoc in our group! Alvaro came with us from Leipzig to continue as a postdoc. Vladi is from the university of Belgrade. He will be 50% in our group and spend 50% of his time … Continue reading
Our HAR1 paper is published
Part of Bia’s PhD project was the analysis of HAR1 evolution. HAR1 is the fastest evolving sequence in the human genome and is part of two overlapping long non-coding RNAs. Bia’s paper “Temporal ordering of substitutions in RNA evolution: Uncovering … Continue reading
Marko Dunjic joins our group
Marko, a highly talented student from Belgrade, Serbia is joining our group for an internship. He is interested in the molecular causes of psychiatric disorders. During his half a year internship he will explore the evolution of long non-coding RNAs … Continue reading
New comparative network method published
Our paper “A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma” was published in PLoS Computational Biology. This was a collaborative work with the group of Eivind Almaas in Trondheim, Norway, lead by … Continue reading