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PhD students in Leipzig finished

For almost two years our group was split between the University Leipzig and the Freie Universitaet Berlin. Now PhD students in Leipzig have finished and moved on to their next research groups: Bia defended in September 2018 and is now … Continue reading

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Ama finished her Master thesis

Ama handed in her Master thesis on the functional evolution of the transcription factor ZEB2. She analyzed RNA-Seq and ChIP-Seq data obtained from three different primate species to detect human specific ZEB2 target genes and functions. Congratulations, Ama!

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New test for selection of RNA secondary structures

Bia developed a test for selection of non-coding RNAs. Her test uses the RNA secondary structure as proxy for its function. In contrast to previous work, she cannot only asses negative selection but also pinpoint structures with lineage specific changes … Continue reading

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Two new lizard genomes

Rohit published his results on the comparison of two lizard genomes: Lacerta viridis and Lacerta bilineata. He sequenced both genomes with Illumina and PacBio, performed de-novo assemblies. The high quality assemblies allowed him to assess genome divergence, structural variations, and … Continue reading

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wTO package for network analysis

Deisy turned our method for calculating weighted topological overlap (wTO) networks into an R package and published it in BMC Bioinformatics. The method was developed by Eivind Almaas for describing a transcription factor network in the prefrontal cortex of humans … Continue reading

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Paper on human neurogenesis

Our group contributed to a research project of Volker Busskamp’s lab on the role of miR-124 during human neurogenesis. Deisy uncovered a transcription factor network that is involved in the differentiation of neurons from induced pluripotent stem cells and determined … Continue reading

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Network evolution paper

Stefano’s paper on the evolution of the transcription factor network in the primate prefrontal cortex has been published in GBE. While the functional output of that network seems to be conserved across the investigated primates, the network has evolved more … Continue reading

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EVOP moved to the FU

After six successful editions of our Programming for Evolutionary Biology course in Leipzig, we are currently running the first edition at the FU. The outline and philosophy of the course stayed the same; just the location changed. We, organizers, lecturers, … Continue reading

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New Postdoc: Vladimir Jovanovic

We are welcoming the second postdoc in our group! Alvaro came with us from Leipzig to continue as a postdoc. Vladi is from the university of Belgrade. He will be 50% in our group and spend 50% of his time … Continue reading

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Our HAR1 paper is published

Part of Bia’s PhD project was the analysis of HAR1 evolution. HAR1 is the fastest evolving sequence in the human genome and is part of two overlapping long non-coding RNAs. Bia’s paper “Temporal ordering of substitutions in RNA evolution: Uncovering … Continue reading

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