Category Archives: Uncategorized
Laura Schmidt joined our team to work on gene regulatory factors with human specific changes. She will use primate iPSC to comparatively investigate how such factors might have contributed to unique pathways and expression patterns during human brain development.
On February 24th 2022 we gave a talk about our work for the general public at the Urania in Berlin. More than 100 people joined online and about 50 people had been in the auditorium. The talk is now available … Continue reading
Yao-Chung has developed an R package called TEKRABber to compare relationships between transposable elements (TEs) and genes between species. It is now available from Bioconductor:https://bioconductor.org/packages/3.15/bioc/html/TEKRABber.html. Using RNA-Seq data, the package is normalizing expression values for genes and TEs across species … Continue reading
Finally: After waiting for more than four years, we can start our first work in our brand new wetlab!
Because evolutionary changes in gene regulatory factors (GRFs), such as transcription factors, can have a big impact on changing the phenotype between species, we set out to test all human GRFs proteins for positive selection within primates. Using information from 27 … Continue reading
In an international collaboration we investigated the evolution of tissue-specific genes in the Lacerta viridis complex (European green lizard). We had sequenced and analyzed the genomes of three species/lineages and detected gene flow between the Adriatic lineage and L. viridis, suggesting that the evolutionary … Continue reading
We have been featured in the German newspaper Tagesspiegel. Here is the English translation of that article.
Our paper about CoDiNA, a method for comparing coexpression networks, has been accepted for publication by PLoS One. To our knowledge, it is the first method that allows for a comparison of transcriptome-wide networks and of as many networks as … Continue reading
Yao-Chung is finally present in Berlin. Welcome Yao-Chung!