Category Archives: Uncategorized
TEKRABber manuscript submitted to bioRxiv
We submitted our manuscript on our study of functional relationships between KRAB-ZNF genes and transposable elements (TEs) to bioRxiv: “Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease”. In this work, Yao … Continue reading
Manuscript on “mtDNA “Nomenclutter” submitted to PCI
You have submitted your preprint entitled mtDNA “Nomenclutter” and its Consequences on the Interpretation of Genetic Data” to PCIEvolBiol, the Peer Community In for Evolutionary Biology. Baja and Vanessa describe very clearly the history of the nomenclature of human mitochondrial haplogroups, its … Continue reading
We finally have a new TA: Anne
We are happy to announce that we could finally hire Anne as our new technician. We are getting up to speed with our experiments 🙂
Marula started her PhD
We have a new PhD student, Marula Mathew, who is strengthening the wetlab site of our team. Welcome Marula!
Laura started as new PhD student
Laura Schmidt joined our team to work on gene regulatory factors with human specific changes. She will use primate iPSC to comparatively investigate how such factors might have contributed to unique pathways and expression patterns during human brain development.
Talk at Berlin Brains
On February 24th 2022 we gave a talk about our work for the general public at the Urania in Berlin. More than 100 people joined online and about 50 people had been in the auditorium. The talk is now available … Continue reading
TEKRABber R package in Bioconductor
Yao-Chung has developed an R package called TEKRABber to compare relationships between transposable elements (TEs) and genes between species. It is now available from Bioconductor:https://bioconductor.org/packages/3.15/bioc/html/TEKRABber.html. Using RNA-Seq data, the package is normalizing expression values for genes and TEs across species … Continue reading
Starting our wetlab
Finally: After waiting for more than four years, we can start our first work in our brand new wetlab!
Paper on Evolution of Gene Regulatory Factors in primates
Because evolutionary changes in gene regulatory factors (GRFs), such as transcription factors, can have a big impact on changing the phenotype between species, we set out to test all human GRFs proteins for positive selection within primates. Using information from 27 … Continue reading
Paper on evolution of tissue specifically expressed genes is out
In an international collaboration we investigated the evolution of tissue-specific genes in the Lacerta viridis complex (European green lizard). We had sequenced and analyzed the genomes of three species/lineages and detected gene flow between the Adriatic lineage and L. viridis, suggesting that the evolutionary … Continue reading