Category Archives: Uncategorized
Programming for Evolutionary Biology
We are currently running our fifth “Programming for Evolutionary Biology” course in Leipzig. We are taking the students of our course on a tour on analyzing Next-Generation-Sequencing data, genome annotation, population genomics, phylogenomics, gene expression evolution, biological networks, and other … Continue reading
Our paper on human specific transcriptional regulation accepted
Our paper on the evolution of binding sites of the transcription factor GABPa has been accepted for publication in MBE. This work was originally started by Robert Querfurth at the Max-Planck-Institute for Molecular Genetics in Berlin. Alvaro and I got … Continue reading
Our paper on “The Relativity of Biological Function” is accepted
When we started writing this paper we were inspired by the debate about the question of how much of the human genome is functional. Estimates for that proportion range from 5% to 90%, a huge difference that obviously cannot be … Continue reading
Programming for Evolutionary Biology 2015
Registration just opened for the 4th Programming for Evolutionary Biology course. Based on our very successful previous courses we again put together a comprehensive program for learning programming skills to perform analysis of genomics and evolutionary data. Check out our … Continue reading
We are in the News!
Our local newspaper published an article about us and two more research groups who received together over one million Euro to investigate the functions of long non-coding RNAs in the human nervous system. Our main goal is to understand how … Continue reading
Programming for Evolutionary Biology in Colombia
Many greetings from Bogota, where we are currently holding our first Programming for Evolutionary Biology course in the Americas. Clara Isabel Bermúdez Santana and her TAs Cristian, Alejandro, and Diego, as well as her students from the Universidad Nacional de … Continue reading
Special journal issue on Human Evolution
Aida Andres and I have put together a special journal issue with papers on human evolution for the journal Current Opinion in Genetics & Development. Inviting the authors for 19 articles, editing, and coordinating this special issue has been an … Continue reading
Paper on phased human genomes published
In our paper Hoehe et al. on “Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes” published in Nature Communications we describe the extent of sequence variation that exists between the two alleles of human individuals. Surprisingly, many … Continue reading
BioVis – Design contest on RNA secondary structure visualization
When we compared the secondary structures of the non-coding RNA HAR1 between primate species and wanted to represent our results at Bia’s poster at the ISMB conference this year, we realized that it is quite challenging to find a good … Continue reading
Sandra and Lisa finished their Master theses
Sandra and Lisa, both turned their projects into very interesting and well-conducted Masters theses. Sandra worked on the “Evolutionary comparison of KAP1 binding sites between humans and chimpanzees” and Lisa on the “Functional characterization of ZNF542 and ZEB2 in primates”. … Continue reading